Not at all
My USB ports work well! Besides,very often, I use a 5Volt supplementary PSU..and the mainboard is OK
The drive on the matter seems perfect(without generating crashes or BSODs) , if installed into an USB-IDE interface, obviously, I consider only the right partition of 180GB.
I've several Compaq Evo n620C that I employ for any kind of software tests
These old laptops are very versatile and suitable for these purposes.
I've installed Windows 7 SP1 Ultimate , just on a 620C and anything is perfectly working, included graphic card!!! I've also installed, in another 620c, MAC OS X 4.8 and it's nearly perfect and fast: the only ecception is the right audio channel which is not so good, like the left one! The main difficulty has been in finding a correct driver for the ethenet card, but after some attempts I succeeded in installing the right driver.
I keep on handling this HDD, only because is an ATA drive large sized, therefore more espensive than a SATA hdd!
Regards