Is there a way to disable Load/Unload cycle counter on system level or something like this?

Or as can I understand I need to disable APM. Is there a solution 4 this?

Have you tried hdparm? HDDScan?

In any case, your drive appears to be parking its heads every 3 minutes, which seems reasonable to me. In fact at the present rate it will be at least 5 years of 24/7 operation before your drive hits the SMART threshold for the Load/Unload Cycle Count.

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A backup a day keeps DR away.

No I don't. I hope this can be doing by Windows native tools. But I see I'm wrong.

In anyway I used HDDScan and seems to be it's works. Thank for advise.

QuietHDD is another application that can control APM and AAM:
http://sites.google.com/site/quiethdd/

hdparm can run from a command line, so it can autorun (and autoexit) during bootup.

"This directory contains binary packages of the Windows (2000, XP, 2003) version of hdparm":
http://hdparm-win32.dyndns.org/hdparm/

I don't know if the above binaries are suitable for Win 7.

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A backup a day keeps DR away.

One thing is to have the drive always on (so the load/unload counter doesn't increase), another thing is preventing it from increasing doing whatever you want with the drive